The push and pull of power

By G. Jeffrey MacDonald

In the mid-1990s, executives at pharmaceutical giant Bristol-Myers Squibb were counting on big results from Capoten, a hot new drug for lowering blood pressure, when unwelcome news crossed their desks.

Studies of pregnant women were beginning to suggest Capoten could cause serious problems in the fetus. Top company executives mulled their options carefully: Should the drug be pulled? Should a warning label immediately be applied?…

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